Usually 50 to 90% of vitamin D is produced by sunshine exposure of skin and the remainder comes from the diet. The natural diet, that most human consume, contain little vitamin D.
Vitamin D Receptors, also called VDR, are widespread in nearly all body tissues and important organs. These receptors are pivotal molecules that mediates inter-organ communication to broaden the application of vitamin D signal modulators. Binding of VDR and Vitamin D molecules releases signals that ensure proper functioning of these tissues and organs.
Vitamin D3 deficiency can result in obesity, diabetes, hypertension, depression, fibromyalgia, chronic fatigue syndrome, osteoporosis and neuro-degenerative diseases including Alzheimer’s disease.
Vitamin D deficiency may even contribute to the development of cancers, especially breast, prostate, and colon cancers. Current research have found low levels of vitamin D in various patients suffering from seventeen varieties of different cancers, heart disease, stroke, autoimmune diseases, birth defects, and periodontal disease. Vitamin D3 is believed to play a role in controlling the immune system (possibly reducing one’s risk of cancers and autoimmune diseases), increasing neuromuscular function and improving mood, protecting the brain against toxic chemicals, and potentially reducing pain.